Hot Topic Commentary

• Therapeutic Use of Viruses: Newcastle Disease Virus HK84 Oncolytic Treatment for Hepatocellular Carcinoma   

  Leonardo Baiocchi, Heather Francis, Gianfranco Alpini

  

Letter to the Editor

• Effect of Lactate on Epigenetic Regulation in the Development of Hepatitis B Virus-related Hepatocellular Carcinoma   

  Shahab Mahmoudvand, Somayeh Shokri

  

Original Article

• A Multipathogen Bile Sample-based PCR Assay Can Guide Empirical Antimicrobial Strategies in Cholestatic Liver Diseases

  Michael Jahn, Mustafa K Özçürümez, Sebastian Dolff, Hana Rohn, Dominik Heider, Alexander Dechêne, Ali Canbay, Peter M. Rath, Antonios Katsounas

  
• Highly Increased Levels of Inter-α-inhibitor Heavy Chain 4 (ITIH4) in Autoimmune Cholestatic Liver Diseases

  Tea Lund Laursen, Lars Bossen, Rasmus Pihl, Anne Troldborg, Thomas Damgaard Sandahl, Annette Gudmann Hansen, Trine Folserass, Mette Vesterhus, Henning Grønbæk, Steffen Thiel

  
• Liver Function Derangement in Patients with Severe Fever and Thrombocytopenia Syndrome

  Sihong Lu, Ling Xu, Boyun Liang, Hua Wang, Tong Wang, Tiandan Xiang, Sumeng Li, Lei Fan, Junyuan Li, Cheng Peng, Xin Zheng

  

• A Prognostic Nomogram with High Accuracy Based on 2D-SWE in Patients with Acute-on-chronic Liver Failure

  Lili Wu, Jieyang Jin, Taicheng Zhou, Yuankai Wu, Xinhua Li, Xiangyong Li, Jie Zeng, Jinfen Wang, Jie Ren, Yutian Chong, Rongqin Zheng

  
• Development of a Widely Applicable and Simple Prognostic Score for Patients with Acute-on-chronic Liver Failure

  Zhenjun Yu, Yu Zhang, Yuhan Li, Feng Zhou, Manman Xu, Shaoli You, Yu Chen, Bing Zhu, Ming Kong, Fangjiao Song, Shaojie Xin, Zhongping Duan, Tao Han, China Network for Severe Liver Diseases

  
• Regulatory Effect of JAK2/STAT3 on the Immune Function of Endotoxin-tolerant Dendritic Cells and its Involvement in Acute Liver Failure

  Yukai Chen, Chaochen Hou, Naibin Yang, Yanyan Yang, Youran Chen, Deyong Kong, Yuchun Jiang, Minghao Lin, Sijie Zheng, Shanshan Li, Mingqin Lu

  

• Regional and National Trends of Adult Living Donor Liver Transplantation in the United States Over the Last Two Decades

  Saleh A. Alqahtani, Ahmet Gurakar, Hani Tamim, Thomas D. Schiano, Alan Bonder, Zachary Fricker, Marwan Kazimi, Devin E. Eckhoff, Michael P. Curry, Behnam Saberi

  

• Efficacy and Safety of Aspirin for Prevention of Hepatocellular Carcinoma: An Updated Meta-analysis

  Lun-Jie Yan, Sheng-Yu Yao, Hai-Chao Li, Guang-Xiao Meng, Kai-Xuan Liu, Zi-Niu Ding, Jian-Guo Hong, Zhi-Qiang Chen, Zhao-Ru Dong, Tao Li

  
• A Prognostic Nomogram for Hepatocellular Carcinoma Based on Wound Healing and Immune Checkpoint Genes

  Beiyuan Hu, Xiaotian Shen, Wei Qin, Lan Zhang, Tiantian Zou, Qiongzhu Dong, Lun-Xiu Qin

  
• Establishment of a Prognostic Model for Hepatocellular Carcinoma Based on Bioinformatics and the Role of NR6A1 in the Progression of HCC

  Zhong-Hua Lin, Jie Zhang, Li-Kun Zhuang, Yong-Ning Xin, Shi-Ying Xuan

  
• Upregulation of TMCO3 Promoting Tumor Progression and Contributing to the Poor Prognosis of Hepatocellular Carcinoma

  Tianxing Dai, Linsen Ye, Mingbin Deng, Guozhen Lin, Rongqiang Liu, Haoyuan Yu, Wei Liu, Yang Yang, Guoying Wang

  
• A Novel mRNA Signature Related to Immunity to Predict Survival and Immunotherapy Response in Hepatocellular Carcinoma

  Chenhao Zhou, Jialei Weng, Yuan Gao, Chunxiao Liu, Xiaoqiang Zhu, Qiang Zhou, Chia-Wei Li, Jialei Sun, Manar Atyah, Yong Yi, Qinghai Ye, Yi Shi, Qiongzhu Dong, Yingbin Liu, Mien-Chie Hung, Ning Ren

  

• Premorbid Steatohepatitis Increases the Seriousness of Dextran Sulfate Sodium-induced Ulcerative Colitis in Mice

  Meng-Yu Wang, Zi-Xuan Wang, Lei-Jie Huang, Rui-Xu Yang, Zi-Yuan Zou, Wen-Song Ge, Tian-Yi Ren, Jian-Gao Fan

  

• Protective Effect of Neonatal Hepatitis B Vaccine Against HBV Breakthrough Infection in Children with Leukemia: A Real-world Study

  Yuting Yang, Jianwen Xiao, Xiuyu Zhang, Hui Yang, Zhenzhen Zhang, Hongmei Xu, Ailong Huang, Yao Zhao

  

Review Article

• Reactive Oxygen Species and Oxidative Stress in the Pathogenesis of MAFLD   

  Kathleen Clare, John F. Dillon, Paul N. Brennan

  
• Pregnancy and Metabolic-associated Fatty Liver Disease: A Clinical Update   

  Sherouk Fouda, Madhu Mathew Vennikandam, Joseph M. Pappachan, Cornelius J. Fernandez

  
• Hepatocellular Carcinoma in Non-alcoholic Fatty Liver Disease: Current Progresses and Challenges   

  Yu-Xian Teng, Si Xie, Ping-Ping Guo, Zhu-Jian Deng, Zi-Yi Zhang, Wei Gao, Wan-Guang Zhang, Jian-Hong Zhong

  
• Pharmacotherapy for Non-alcoholic Fatty Liver Disease Associated with Diabetes Mellitus Type 2   

  Emmanouil S. Koullias, John Koskinas

  
• HBeAg-negative Patients with Chronic Hepatitis B Virus Infection and Normal Alanine Aminotransferase: Wait or Treat?   

  Qiuju Sheng, Ning Wang, Chong Zhang, Yaoxin Fan, Yanwei Li, Chao Han, Ziyi Wang, Shuqi Wei, Xiaoguang Dou, Yang Ding

  
• Portal Hypertension in Nonalcoholic Fatty Liver Disease: From Pathogenesis to Clinical Practice   

  Saut Horas H. Nababan, Cosmas Rinaldi Adithya Lesmana

  
• Endoscopic Bariatric and Metabolic Therapies for Liver Disease: Mechanisms, Benefits, and Associated Risks   

  Mengting Ren, Xinxin Zhou, Lu Lv, Feng Ji

  
• Prospect of Animal Models for Acute-on-chronic Liver Failure: A Mini-review   

  Hozeifa Mohamed Hassan, Jun Li

  

Guideline

• Management Algorithm for Prevention of Mother-to-child Transmission of Hepatitis B Virus (2022)   

  Zhihua Liu, Zhongdan Chen, Fuqiang Cui, Yang Ding, Yunfei Gao, Guorong Han, Jidong Jia, Jie Li, Zengde Li, Yingxia Liu, Qing Mao, Ailing Wang, Wei Wang, Lai Wei, Jianhong Xia, Qing Xie, Xizhong Yang, Xueru Yin, Hua Zhang, Liaoyun Zhang, Wenhong Zhang, Hui Zhuang, Xiaoguang Dou, Jinlin Hou

  

Corrigendum

• Corrigendum: Chronic Hepatitis B Infection with Low Level Viremia Correlates with the Progression of the Liver Disease