Original Article

• Serum Iron Overload Activates the SMAD Pathway and Hepcidin Expression of Hepatocytes via SMURF1

  Ning Zhang, Pengyao Yang, Yanmeng Li, Qin Ouyang, Fei Hou, Guixin Zhu, Bei Zhang, Jian Huang, Jidong Jia, Anjian Xu

  
• Trends in Mortality of Cirrhosis in China: An Analysis of the China Death Surveillance Database from 2008 to 2020

  Xiaoxiao Wang, Huixin Liu, Jinlei Qi, Lijun Wang, Peng Yin, Feng Liu, Lai Wei, Yu Wang, Maigeng Zhou, Huiying Rao

  
• Impact of Onset Time, Number, Type, and Sequence of Extrahepatic Organ Failure on Prognosis of Acute-on-chronic Liver Failure

  Shaotian Qiu, Qian Zhang, Jiaxuan Hu, Lewei Wang, Rui Chen, Yingying Cao, Fang Liu, Zhenjun Yu, Caiyan Zhao, Liaoyun Zhang, Wanhua Ren, Shaojie Xin, Yu Chen, Zhongping Duan, Tao Han

  

• BTF3L4 Overexpression Mediates APAP-induced Liver Injury in Mouse and Cellular Models

  Junchao Lin, Aqiang Fan, Zhujin Yifu, Qibing Xie, Liu Hong, Wei Zhou

  

• Prognostic Biomarkers for Hepatocellular Carcinoma Based on Serine and Glycine Metabolism-related Genes

  Xufan Cai, Fang Xu, Zhaohong Wang, Hui Chen, Shengzhang Lin

  

Review Article

• Approaching the Sarcopenic Patient with Nonalcoholic Steatohepatitis-related Cirrhosis   

  Paolo Gallo, Valentina Flagiello, Andrea Falcomatà, Giulia Di Pasquale, Giorgio D’Avanzo, Francesca Terracciani, Antonio Picardi, Umberto Vespasiani-Gentilucci

  
• Immune Regulatory Networks and Therapy of γδ T Cells in Liver Cancer: Recent Trends and Advancements   

  Kun-Li Yin, Kai-Jian Chu, Ming Li, Yu-Xin Duan, Yan-Xi Yu, Mei-Qing Kang, Da Fu, Rui Liao

  
• Improving the Conversion Success Rate of Hepatocellular Carcinoma: Focus on the Use of Combination Therapy with a High Objective Response Rate   

  Qi-Feng Chen, Song Chen, Minshan Chen, Ning Lyu, Ming Zhao

  
• Progress in Biomarkers Related to Biliary Atresia   

  Fanyang Kong, Rui Dong, Gong Chen, Song Sun, Yifan Yang, Jingying Jiang, Lingdu Meng, Huifen Chen, Jiajie Zhu, Shan Zheng

  
• Genetics of Gallstone Disease and Their Clinical Significance: A Narrative Review   

  Christopher J. Costa, Minh Thu T. Nguyen, Haleh Vaziri, George Y. Wu

  

Illuminating and Instructive Clinical Case

• Late-onset Cholestasis with Paucity of Portal Area Secondary to HNF1β Deficiency in Adulthood: A Case Report   

  Xuemei Zhang, Kun Liu, Xiaona Lu, Wenlan Zheng, Jia Shi, Shihan Yu, Hai Feng, Zhuo Yu