Original Article

• Centromere Protein I, a Cell Cycle Checkpoint Gene, Accelerates Tumor Progression via the Hippo Pathway and Mediates Immune Escape in Hepatocellular Carcinoma

  Risheng He, Yi Xu, Pengbo Zhang, Liang Yu, Jian Ma, Yunfu Cui

  

• Fecal Microbiome and Bile Acid Profiles Differ in Preterm Infants with Parenteral Nutrition-associated Cholestasis

  Ellen S. Wagner, Kaitlyn Oliphant, Mark D’Souza, Wilfredo Cruz-Ayala, Ruba K. Azzam, Bree Andrews, Erika C. Claud

  

• PDK4 Regulates Inflammatory Injury in Acute-on-chronic Liver Failure by Phosphorylating STAT1-mediated M1 Polarization of Macrophages

  Shilong Dong, Luyuan Ma, Chuan Shen, Ruolan Gu, Xinyang Li, Ying Xiao, Caiyan Zhao

  

Review Article

• Nutrient-stimulated Hormone-based Therapies: A New Frontier in the Prevention and Management of MASH-associated Hepatocellular Carcinoma   

  Richard Phillips, Yuk Ting Ma, Wasim Hanif, Tahir Shah, Shivan Sivakumar

  
• Protein Induced by Vitamin K Absence or Antagonist II in Primary Liver Cancer: Basic Research Insights and Clinical Applications   

  Xin Zhang, Rong Wang, Bin Niu, Liaoyun Zhang

  
• Current and Emerging Issues in Familial Hypobetalipoproteinemia-related Steatotic Liver Diseases   

  Tian-Wen Lou, Tian-Yi Ren, Jian-Gao Fan

  
• Quality and Quantity? The Clinical Significance of Myosteatosis in Various Liver Diseases: A Narrative Review   

  Jie Yang, Qing Liu, Chao Sun

  

Consensus

• Expert Consensus on Clinical Applications of Fecal Microbiota Transplantation for Chronic Liver Disease (2025 edition)   

  Yongjian Zhou, Li Yang, Yuemin Nan, Liver Related Digestive Diseases Group, Chinese Society of Hepatology, Chinese Medical Association

  

Illuminating and Instructive Clinical Case

• Human Albumin-enriched Peritoneal Dialysis: A Novel Approach to Manage Refractory Ascites and Kidney Dysfunction in Decompensated Advanced Chronic Liver Disease   

  Mario Romeo, Silvio Borrelli, Marcello Dallio, Carlo Garofalo, Fiammetta Di Nardo, Paolo Vaia, Carmine Napolitano, Luca De Nicola, Alessandro Federico

  

Research Letter

• Longitudinal Profile of HBsAg Isoforms and Circulating Immune Complexes in the Natural History of Chronic Hepatitis B Infection   

  Lung-Yi Mak, Mark Anderson, Tiffany Fortney, Danny Ka-Ho Wong, Rex Wan-Hin Hui, Wai-Kay Seto, Gavin Cloherty, Man-Fung Yuen

  
• Screening for Mutations Causing ACOX2 Deficiency-associated Hypertransaminasemia in Patients with Cryptogenic Liver Injury   

  Elisa Herraez, Maria J. Monte, Marta Alonso-Peña, Jesus Prieto, Luis Bujanda, Milagros Muñoz-Chimeno, Ana Avellon, Jose J.G. Marin

  

Reviewer Acknowledgement

• 2025 Reviewer Acknowledgement   

  Editorial Office of Journal of Clinical and Translational Hepatology