Original Article

• Serum miR-381-3p: Diagnostic Role and Mechanisms in Liver Transplant Ischemia-reperfusion Injury

  Xiaobin Chi, Zerun Lin, Zhijian Chen, Jianda Yu, Yongbiao Chen, Honghuan Lin, Qiucheng Cai, Lizhi Lv

  

• Association of Changes in Portal Insulin with Immunometabolism During and After Hepatitis C Virus Infection

  Matthew G. Menkart, Jenna L. Oringher, Moumita Chakraborty, James A. Haddad, Gabriella M. Quinn, Grace Zhang, Elizabeth C. Townsend, Kareen L. Akiva, Lisa Scheuing, Anjali Rai, Shakuntala Rampertaap, Sergio D. Rosenzweig, Christopher Koh, Rebecca J Brown, Regina Umarova, Elliot B. Levy, David E. Kleiner, Rabab O. Ali, Ohad Etzion, Rownock Afruza, Theo Heller

  
• Eight-year Results from Two Randomized Phase 3 Trials of Tenofovir Alafenamide for Chronic Hepatitis B Virus Infection in China

  Jinlin Hou, Qin Ning, Zhongping Duan, Yu Chen, Qing Xie, Lunli Zhang, Shanming Wu, Hong Tang, Jun Li, Feng Lin, Yongfeng Yang, Guozhong Gong, Yanwen Luo, Yan Chen, Frida Abramov, Leland J. Yee, Hongyuan Wang, Roberto Mateo, Tahmineh Yazdi, Irina Botros, Chengwei Chen, Yan Huang, Mingxiang Zhang, Jidong Jia

  
• Traditional and Novel Virologic Markers for Functional Cure and HBeAg Loss with Pegylated Interferon in Chronic Hepatitis B: A Systematic Review and Meta-analysis

  Ying Zhang, Long-Fei Wang, Jing Chen, Mindie H. Nguyen, Qi Zheng

  

• Intestinal Candida albicans is Associated with Subclinical Coronary Atherosclerosis in Metabolic Dysfunction-associated Steatotic Liver Disease with Cirrhosis

  Nantawat Satthawiwat, Suthida Visedthorn, Pakorn Ruengket, Prangwalai Chanchaem, Pattida Kongsomboonchoke, Monravee Tumkosit, Pairoj Chattranukulchai, Sunchai Payungporn, Pisit Tangkijvanich

  
• Metabolic Risk Factors and Clinical Presentations of Metabolic Dysfunction-associated Steatotic Liver Disease Using Data from the All of Us Research Program

  Ke-Qin Hu, Seyedeh Neelufar Payrovnaziri, Argyrios Ziogas, Steven Hiek, Kuangda Shan, Tevan Luong, Jenny Fang, Hoda Anton-Culver

  
• Bidirectional Regulation between Metabolic Dysfunction-associated Steatotic Liver Disease and Sarcopenia via Liver-muscle Crosstalk

  Yeyu Song, Yameng Liu, Jie Jiang, Youjie Zheng, Zixuan Wang, Cen Xie, Jian-Gao Fan

  

• Cathepsin K Alleviates Liver Fibrosis by Inhibiting the TGF-β/Smad Signaling Pathway and Inducing Hepatic Stellate Cell Apoptosis

  Zhandong Lin, Yue Shi, Mengjiao Sun, Jiawei Cui, Dandan Zhao, Yaoyao Mao, Congyue Zhang, Ying Zhang, Qianqian Zheng, Yukai Chen, Shaoya Li, Yuemin Nan

  

• Prognostic Nutritional Index Predicts Outcomes in Hepatocellular Carcinoma Treated with Atezolizumab and Bevacizumab: A Propensity Score-matched Analysis

  Yuan-Hung Kuo, Wei Teng, Yen-Hao Chen, Po-Ting Lin, Tsung-Han Wu, Chung-Wei Su, Wei-Ting Chen, Chen-Chun Lin, Chao-Hung Hung, Sheng-Nan Lu, Shi-Ming Lin, Jing-Houng Wang, Chun-Yen Lin

  

Review Article

• Advancements in Understanding the Role of Oxylipins in Liver Injury and Liver Failure

  Xiaoling Su, Aidiya Yimamu, Sheng Tu, Mengxuan Hao, Haiyang Bi, Ting Liu, Minmin Zhang, Xianbin Xu, Xia Yu, Zhenyu Shan, Jifang Sheng, Yu Shi, Zeyu Sun

  
• Congenital Portosystemic Shunts – A Review

  George Y. Wu

  
• Risk Factors and Biomarkers for Immune Checkpoint Inhibitor-mediated Hepatotoxicity: Emerging Insights and Future Perspectives

  Zaoqin Yu, Yanjiao Xu, Wei Li, Yingjie Hu, Chengliang Zhang

  
• Repurposing SGLT2 Inhibitors for Cirrhotic Ascites: From Mechanistic Research to Clinical Exploration

  Yuan Gao, Yunyi Gao, Dong Ji, Zhongjie Hu

  
• Tumor Vaccines in Hepatocellular Carcinoma: Advances, Challenges, and the Path Toward Precision Immunotherapy

  Bin Niu, Jun Xu, Liaoyun Zhang

  

Hot Topic Commentary

• Immune Checkpoint Inhibitor–induced Liver Injury: A Critical Appraisal of Treatment and Rechallenge Controversies

  Fernando Bessone, Nelia Hernandez