Editorial

• Newcastle Disease Virus/HK84: Next Potential Star for Targeted Immunotherapy of Hepatocellular Carcinoma?   

  Weiyi Huang, Wenjun Chang

  
• Impaired Pulmonary Function as a Potential Contributor to Reduced Exercise Capacity Associated with MAFLD   

  Derrick Michael Van Rooyen, Oyekoya Taiwo Ayonrinde

  

Original Article

• Preoperative Assessment of Abdominal Adipose Tissue to Predict Microvascular Invasion in Small Hepatocellular Carcinoma

  Zongqian Wu, Hong Lu, Qiao Xie, Jie Cheng, Kuansheng Ma, Xiaofei Hu, Liang Tan, Huarong Zhang, Chen Liu, Xiaoming Li, Ping Cai

  
• Irreversible Electroporation for Hepatocellular Carcinoma Abutting the Diaphragm: A Prospective Single-center Study

  Yangyang Ma, Zhixian Chen, Bing Liang, Rongrong Li, Jianyu Li, Zhonghai Li, Mao Lin, Lizhi Niu

  
• A New Prognostic Model Covering All Stages of Intrahepatic Cholangiocarcinoma

  Shuang-Nan Zhou, Shan-Shan Lu, Da-Wei Ju, Ling-Xiang Yu, Xiao-Xiao Liang, Xiao Xiang, Suthat Liangpunsakul, Lewis R. Roberts, Yin-Ying Lu, Ning Zhang

  
• A Nomogram-based Model to Predict Neoplastic Risk for Patients with Gallbladder Polyps

  Xudong Zhang, Jincheng Wang, Baoqiang Wu, Tao Li, Lei Jin, Yong Wu, Peng Gao, Zhen Zhang, Xihu Qin, Chunfu Zhu

  
• A Molecular Hepatocellular Carcinoma Prognostic Score System Precisely Predicts Overall Survival of Hepatocellular Carcinoma Patients

  Jie Jia, Jing Tang

  
• Oncolytic Activity of Wild-type Newcastle Disease Virus HK84 Against Hepatocellular Carcinoma Associated with Activation of Type I Interferon Signaling

  Liming Chen, Yongdong Niu, Jiating Sun, Hong Lin, Guoxi Liang, Min Xiao, Dongmei Shi, Jia Wang, Huachen Zhu, Yi Guan

  
• Expression and Regulatory Network Analysis of Function of Small Nucleolar RNA Host Gene 4 in Hepatocellular Carcinoma

  Jing Cao, Cuicui Xiao, Christ-Jonathan Tsia Hin Fong, Jiao Gong, Danyang Li, Xiangyong Li, Yusheng Jie, Yutian Chong

  
• Prognostic Role and Potential Mechanisms of N6-methyladenosine-related Long Noncoding RNAs in Hepatocellular Carcinoma

  Tianxing Dai, Jing Li, Linsen Ye, Haoyuan Yu, Mingbin Deng, Wei Liu, Hua Li, Yang Yang, Guoying Wang

  

• Vibration-controlled Transient Elastography for Assessment of Liver Fibrosis at a USA Academic Medical Center

  Max Shen, Anna Lee, Jay H. Lefkowitch, Howard J. Worman

  
• KRT17 Promotes the Activation of HSCs via EMT in Liver Fibrosis

  Jing Chen, Si-Jia Ge, Hai-Juan Feng, Shu-Zhen Wu, Ran Ji, Wei-Rong Huang, Wei Huang, Cui-Hua Lu

  

• Interaction of SAMM50-rs738491, PARVB-rs5764455 and PNPLA3-rs738409 Increases Susceptibility to Nonalcoholic Steatohepatitis

  Ke Xu, Kenneth I. Zheng, Pei-Wu Zhu, Wen-Yue Liu, Hong-Lei Ma, Gang Li, Liang-Jie Tang, Rafael S. Rios, Giovanni Targher, Christopher D. Byrne, Xiao-Dong Wang, Yong-Ping Chen, Ming-Hua Zheng

  
• Metabolic Dysfunction-associated Fatty Liver Disease is Associated with Greater Impairment of Lung Function than Nonalcoholic Fatty Liver Disease

  Lei Miao, Li Yang, Li-Sha Guo, Qiang-Qiang Shi, Teng-Fei Zhou, Yang Chen, Huai Zhang, Hui Cai, Zhi-Wei Xu, Shuan-Ying Yang, Hai Lin, Zhe Cheng, Ming-Yang Zhu, Xu Nan, Shuai Huang, Ya-Wen Zheng, Giovanni Targher, Christopher D Byrne, Yu-Ping Li, Ming-Hua Zheng, Cheng-Shui Chen

  

• Risk Factors of Chronic Kidney Disease in Chronic Hepatitis B: A Hospital-based Case-control Study from China

  Yunqi Liu, Ximei Wang, Fuping Xu, Dengren Li, Huimin Yang, Nan Sun, Yu-Chen Fan, Xiangdong Yang

  
• Gamma-glutamyl Transpeptidase to Platelet Ratio Predicts Liver Injury in Hepatitis B e Antigen-negative Chronic Hepatitis B Patients With Normal Alanine Aminotransferase

  Xiang-An Zhao, Jian Wang, Jie Wei, Jiacheng Liu, Guangmei Chen, Li Wang, Guiyang Wang, Juan Xia, Weihua Wu, Shengxia Yin, Xin Tong, Xiaomin Yan, Weimao Ding, Xiaoxing Xiang, Rui Huang, Chao Wu

  

Review Article

• Targeted Mitochondrial Delivery to Hepatocytes: A Review   

  Brent D. Heineman, Xiaocong Liu, George Y. Wu

  
• Metabolic-associated Fatty Liver Disease (MAFLD): A Multi-systemic Disease Beyond the Liver   

  Eda Kaya, Yusuf Yilmaz

  
• Coagulation and Endothelial Dysfunction Associated with NAFLD: Current Status and Therapeutic Implications   

  Doris Ogresta, Anna Mrzljak, Maja Cigrovski Berkovic, Ines Bilic-Curcic, Sanja Stojsavljevic-Shapeski, Lucija Virovic-Jukic

  
• Glutaminolysis-ammonia-urea Cycle Axis, Non-alcoholic Fatty Liver Disease Progression and Development of Novel Therapies   

  Ángela Rojas, María Rosario García-Lozano, Antonio Gil-Gómez, Manuel Romero-Gómez, Javier Ampuero

  
• Recent Progress and Future Direction for the Application of Multiomics Data in Clinical Liver Transplantation   

  Zhengtao Liu, Jun Xu, Shuping Que, Lei Geng, Lin Zhou, Adil Mardinoglu, Shusen Zheng

  
• Redefinition of Fatty Liver Disease from NAFLD to MAFLD through the Lens of Drug Development and Regulatory Science   

  Yasser Fouad, Melissa Palmer, Minjun Chen, Arie Regev, Rajarshi Banerjee, Rob Myers, Robert Riccio, Richard Torstenson, Ramy Younes, Puneet S. Arora, Henrik Landgren, Morten A. Karsdal, Martin Blake, David A. Shapiro, Hans-Juergen Gruss, Muhammad Y. Sheikh, Dina Attia, Steven Bollipo, Alastair D. Smith, Bradley Freilich, Robert G. Gish, Detlef Schuppan