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Molecular Mechanisms of Essential Oils in the Treatment of Diseases via Systems Biology

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Topic Editors

Keywords: Essential oils; Systems biology; Traditional medicine; Molecular mechanisms

Essential oils (EOs) are natural products with bioactive functions that are obtained from many plant species, e.g., Lavandula angustifolia, and plant parts e.g., flower and leaf, through extraction methods such as hydro-distillation, steam distillation, cold pressing, etc. Such techniques can be dated back to ancient Egyptian and Greek times. EOs represent an important part of traditional medicine and have practical applications in the treatment of human infectious diseases and mental disorders. Although many EOs are effective in disease treatment, the specific pharmacological mechanisms underlying their effects remain unclear due to their complex compositions. Previous studies have attempted to apply pharmaceutical analysis techniques such as HPLC and MALDI-TOF mass spectrometry to elucidate the compositions of EOs. Although these methods are effective at identifying the components of EOs, they provide limited information regarding the mechanisms of the bioactive functions of EOs. In recent years, both molecular biology and computational analyses have emerged as convenient and appropriate approaches for studying the molecular mechanisms of traditional medicines. Due to its multi-compound, multi-target, multi-pathway and multi-disease mode of action, systems biology technology hold the potential for thoroughly understanding the pharmacological effects of EOs in the context of any specific disease.

In this special issue, we encourage authors to submit their studies on the functions of EOs in disease treatment via systems biology methods involving both computational and experimental techniques. The special issue will contribute to a better understanding of the molecular mechanisms responsible for the functions of EOs in disease treatment.

Priority will be given with the same high standards of peer review and publication process for these articles. All publications will open free access to all readers. We guarantee that all accepted papers related to Treatment of Diseases via Systems Biology will be highlighted in a special section on our website.

Publication date: An article will be published online as soon as it is accepted.

Guest Editor-in-Chief

Liang Wang

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Principal Investigator, Laboratory Medicine, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, China

Co-Guest Editor

Yin-Yin Wang

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Associate Professor, School of Traditional Chinese Pharmacy, China Pharmaceutical University

Co-Guest Editor

Xin Liu

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Associate Professor, Department of Intelligent Medical Engineering, School of Medical Informatics and Engineering, Xuzhou Medical University, Xuzhou, Jiangsu Province, China

Co-Guest Editor

Yu-Dong Zhang

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Lecturer, The First School of Clinical Medicine, Xuzhou Medical University, Xuzhou, Jiangsu Province, China

Important Dates

Submission open date: December 8, 2022

Submission deadline: December 31, 2023