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Corrigendum Open Access
Anil K. Philip, Betty Annie Samuel, Bassim A. Mohammed, Hayder A. Al-Aubaidy
Published online July 15, 2025
Journal of Exploratory Research in Pharmacology. doi:10.14218/JERP.2024.00027C
Corrigendum Open Access
Benjamin O. Ezema, Chijioke Nwoye Eze, Thecla Okeahunwa Ayoka, Charles Okeke Nnadi
Published online July 15, 2025
Journal of Exploratory Research in Pharmacology. doi:10.14218/JERP.2024.00020C
Corrigendum Open Access
Nilanga Aki Bandara, Dhruv Lalkiya, Ryan Vethanayagam, Quaila-Lee Trang, Srinjoy Ray, Monica Anand, Parsa Khatami, Lea Lough, Anahita Nikmanesh, Malisha Ratnayake, Xuan Randy Zhou, David Harriman, Miles Mannas, Vahid Mehrnoush, Jay Herath
Published online July 15, 2025
Journal of Exploratory Research in Pharmacology. doi:10.14218/JERP.2023.00057C
Corrigendum Open Access
Sunny Rathee, Umesh K. Patil, Sanjay K. Jain
Published online July 15, 2025
Journal of Exploratory Research in Pharmacology. doi:10.14218/JERP.2023.00050C
Corrigendum Open Access
Tomas Koltai, Larry Fliegel
Published online July 14, 2025
Gene Expression. doi:10.14218/GE.2023.00014C
Corrigendum Open Access
Corrigendum Open Access
Seyed Mohammad Hadi Safaei, Mohammadreza Mohammadabadi, Borhan Moradi, Oleksandr Kalashnyk, Nataliia Klopenko, Olena Babenko, Oleksandr Oleksandrovich Borshch, Volodymyr Afanasenko
Published online July 14, 2025
Gene Expression. doi:10.14218/GE.2023.00020C
Mini Review Open Access
Yanjun Hou, Deyin Xing, Zaibo Li
Published online July 14, 2025
Journal of Clinical and Translational Pathology. doi:10.14218/JCTP.2025.00020
Abstract
Mesonephric carcinoma (MC) is a rare type of cervical carcinoma that arises from mesonephric remnants. It is characterized by a mixture of a wide variety of growth patterns and [...] Read more.

Mesonephric carcinoma (MC) is a rare type of cervical carcinoma that arises from mesonephric remnants. It is characterized by a mixture of a wide variety of growth patterns and typically exhibits positive immunoreactivity for GATA binding protein 3, thyroid transcription factor 1, and apical common acute lymphoblastic leukemia antigen. A subset of adenocarcinomas in the uterine corpus and ovary with similar morphology and immunophenotype is classified as mesonephric-like adenocarcinoma (MLA) in the current World Health Organization classification. This review aimed to summarize the clinicopathological features of mesonephric remnants, mesonephric hyperplasia, and MC, provide an update on the current understanding of MLA, and highlight the molecular differences between MC and MLA.

A literature review was conducted on mesonephric remnants, mesonephric hyperplasia, MC, and MLA. The clinicopathological and molecular features were summarized from previously published studies and compared across these entities.

Both MC and MLA exhibit a mixture of growth patterns and show immunoreactivity for GATA binding protein 3, thyroid transcription factor 1, and common acute lymphoblastic leukemia antigen. They commonly harbor genetic alterations in KRAS and NRAS. However, key differences exist between these two entities. MC is associated with mesonephric remnants, whereas no such association has been identified for MLA. Additionally, although KRAS and NRAS mutations are common in both, a subset of MLA cases also harbors PIK3CA and/or PTEN mutations, genetic alterations commonly seen in endometrioid adenocarcinoma.

Although the exact pathogenesis of MLA remains unclear, it is favored to originate from Müllerian-derived epithelium undergoing differentiation along the mesonephric pathway, rather than from true mesonephric remnants. Both MC and MLA tend to follow a relatively aggressive clinical course, underscoring the importance of accurate diagnosis.

Full article
Corrigendum Open Access
Victor M. Color-Aparicio, Angeles C. Tecalco-Cruz, Blanca Delgado-Coello, Marcela Sosa-Garrocho, Jaime Mas-Oliva, Genaro Vázquez-Victorio, Marina Macías-Silva
Published online July 11, 2025
Gene Expression. doi:10.14218/GE.2023.00192C
Corrigendum Open Access
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