Chronic calculous cholecystitis is a common clinical medical disease, which is classified as "hypochondriac pain" in traditional Chinese medicine (TCM). It is caused by liver failure and stagnation of liver qi. Therefore, the method of Soothing the liver and promoting bile flow is often used for regulating and harmonizing qi and blood. This paper discusses its mechanism of action, and points out that Shugan Lidan decoction has great effect on the treatment of chronic calculous cholecystitis, especially in the early treatment of the disease and delaying the progress of the disease, which provides help for the clinical treatment of chronic calculous cholecystitis.