Hydronidone for the Treatment of Liver Fibrosis Associated with Chronic Hepatitis B: Protocol for a Phase 3 Randomized Trial

Xiaobo Cai, Yin Qu, Wen Xie, Yanbin Wang, Mengyu Zhao, Ling Zhang, Ying Luo, Ping Yin, Jun Cheng, Lungen Lu

Published online: March 10, 2025

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doi:10.14218/JCTH.2024.00472

Analysis of the Disease Spectrum Characteristics of Inherited Metabolic Liver Diseases in Two Hepatology Specialist Hospitals in Beijing over the Past 20 Years

Wei Hou, Yuanzhi Huang, Tang Shang, Zheng Wang, Wei Zhang, Kefi Wang, Yinjie Gao, Min Zhang, Sujun Zheng

Published online: March 21, 2025

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doi:10.14218/JCTH.2025.00030

GTF3C2 Promotes the Proliferation of Hepatocellular Carcinoma Cells through the USP21/MEK2/ERK1/2 Pathway

Yani Wu, Yingnan Yang, Youju Zhang, Qiuran Xu, Dongsheng Huang, Kangsheng Tu

Published online: February 11, 2025

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doi:10.14218/JCTH.2024.00386

FTO Promotes Hepatocellular Carcinoma Progression by Mediating m6A Modification of BUB1 and Targeting TGF-βR1 to Activate the TGF-β Signaling Pathway

Lin Zhang, Li Gan, Yuru Lin, Zhechuan Mei, Shengtao Liao

Published online: April 18, 2025

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doi:10.14218/JCTH.2025.00007

Mitochondrial Membrane Potential of CD8⁺ T Cells Predicts Bacterial Infection and Rapid Development of Acute-on-chronic Liver Failure in Cirrhotic Patients

Xixuan Wang, Shuling Chen, Jing Fan, Yuxiang Gong, Hongli Liu, Lili Wang, Xiaoning Feng, Hui Zhou, Wenquan Zeng, Changhua Yi, Caiyun Zhang, Qingfang Xiong, Hao Ren, Yongfeng Yang

Published online: February 25, 2025

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doi:10.14218/JCTH.2024.00452

Inhibition of Cyclooxygenase-2 Upregulates the Nuclear Factor Erythroid 2-related Factor 2 Signaling Pathway to Mitigate Hepatocyte Ferroptosis in Chronic Liver Injury

Zhu Yang, Yang Tai, Tian Lan, Chong Zhao, Jin-Hang Gao, Cheng-Wei Tang, Huan Tong

Published online: March 3, 2025

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doi:10.14218/JCTH.2024.00440

Beyond the Cure: Navigating Hepatocellular Risk and Surveillance after Hepatitis C Eradication in the Direct-acting Antiviral Era

Chencheng Xie, Ashwani K. Singal

Published online: February 8, 2025

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doi:10.14218/JCTH.2024.00499

Non-variceal Extrahepatic Portosystemic Shunts: A Review of Pathogenesis, Diagnosis, and Treatment

Nicole M. Anastasio, George Y. Wu

Published online: March 14, 2025

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doi:10.14218/JCTH.2024.00315

Key Points and Future Directions from the 2024 Chinese Guidelines for Fatty Liver Disease

Maria Tampaki, Evangelos Cholongitas

Published online: March 27, 2025

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doi:10.14218/JCTH.2025.00051

Corrigendum: Ursolic Acid Modulates Estrogen Conversion to Relieve Inflammation in Metabolic Dysfunction-associated Steatotic Liver Disease via HSD17B14

Published online: April 28, 2025

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doi:10.14218/JCTH.2024.00414C