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Online First Articles

The online first articles are peer reviewed, accepted, and are ready for publication, with copyediting, typesetting, proofreading and author review. They have not been assigned to a journal issue; an article will be removed from this page once it is published in a coming issue.

Articles published online first are citable. To cite an article on this page, please refer to the following example:

Yi SG, Sadhu AR, Jones SL, Turner K, Monsour H, Donahue K, et al. The Effect of Adrenal Replacement Therapy on Rates of Fungal Colonization and Mortality in Critically Ill Patients Awaiting Liver Transplantation. J Clin Transl Hepatol. Published online: Sep 15, 2013. doi: 10.14218/JCTH.2013.00007.

Original Article

Global Prevalence, Temporal Trends, and Associated Mortality of Bacterial Infections in Patients with Liver Cirrhosis: A Meta-analysis

Yu-Xin Tian, Bai-Yun Wu, Qi An, Yin-Ping Wu, Jing Zuo, Yee Hui Yeo, Yu-Chen Fan

Published online: October 27, 2025

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doi:10.14218/JCTH.2025.00260

DysUFMylation of SREBP1 Promotes the Progression of Hepatocellular Carcinoma by Reprogramming Lipid Metabolism

Xukang Gao, Zeping Han, Min Xu, Zhutao Wang, Guoqiang Sun, Hao Xiao, Dai Zhang, Shuangjian Qiu, Ning Ren, Chenhao Zhou, Yong Yi

Published online: October 22, 2025

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doi:10.14218/JCTH.2025.00318

Inflammation and Mitochondrial Dysfunction in Cirrhotic Cardiomyopathy: Therapeutic Implications

Yijie Ding, Chengfeng Huang, Guannan Yang, En Liu, Zhongxin Wang, Yong Su, Chaoliang Ge

Published online: October 20, 2025

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doi:10.14218/JCTH.2025.00237

Centromere Protein I, a Cell Cycle Checkpoint Gene, Accelerates Tumor Progression via the Hippo Pathway and Mediates Immune Escape in Hepatocellular Carcinoma

Risheng He, Yi Xu, Pengbo Zhang, Liang Yu, Jian Ma, Yunfu Cui

Published online: September 24, 2025

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doi:10.14218/JCTH.2025.00127

IL1RA+ Myeloid-derived Suppressor Cells Activate Epithelial-mesenchymal Transition to Facilitate Lymphatic and Hepatic Metastasis in Pancreatic Ductal Carcinoma

Huan Liu, Jian Zhang, Shengnan Lv, Xinyu Peng, Han Liu, Haijun Li, Feng Wei

Published online: September 24, 2025

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doi:10.14218/JCTH.2025.00416

Review Article

Protein Induced by Vitamin K Absence or Antagonist II in Primary Liver Cancer: Basic Research Insights and Clinical Applications

Xin Zhang, Rong Wang, Bin Niu, Liaoyun Zhang

Published online: October 28, 2025

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doi:10.14218/JCTH.2025.00377

Nutrient-stimulated Hormone-based Therapies: A New Frontier in the Prevention and Management of MASH-associated Hepatocellular Carcinoma

Richard Phillips, Yuk Ting Ma, Wasim Hanif, Tahir Shah, Shivan Sivakumar

Published online: October 22, 2025

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doi:10.14218/JCTH.2025.00303

The Role of Mitochondrial Complexes in Liver Diseases

Hai An

Published online: October 10, 2025

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doi:10.14218/JCTH.2025.00194

Research Progress on Leptin in Metabolic Dysfunction-associated Fatty Liver Disease

Jian-Li Wang, Yue Xiao, Ming-Long Li, Guo-Li Chen, Miao-Hang Cui, Jin-Long Liu

Published online: September 5, 2025

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doi:10.14218/JCTH.2025.00204

Research Letter

Longitudinal Profile of HBsAg Isoforms and Circulating Immune Complexes in the Natural History of Chronic Hepatitis B Infection

Lung-Yi Mak, Mark Anderson, Tiffany Fortney, Danny Ka-Ho Wong, Rex Wan-Hin Hui, Wai-Kay Seto, Gavin Cloherty, Man-Fung Yuen

Published online: September 24, 2025

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doi:10.14218/JCTH.2025.00379

Impact of Alanine Transaminase Thresholds on Treatment Eligibility of Patients with Chronic Hepatitis B: A Cross-sectional Study of the China Registry of Hepatitis B

Hao Wang, Xiaoqian Xu, Shan Shan, Yuemin Nan, Xiaoyuan Xu, Hui Zhuang, Hong You, Jidong Jia, Yuanyuan Kong, China Registry of Hepatitis B (CR-HepB) Group

Published online: August 22, 2025

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doi:10.14218/JCTH.2025.00252

Screening for Mutations Causing ACOX2 Deficiency-associated Hypertransaminasemia in Patients with Cryptogenic Liver Injury

Elisa Herraez, Maria J. Monte, Marta Alonso-Peña, Jesus Prieto, Luis Bujanda, Milagros Muñoz-Chimeno, Ana Avellon, Jose J.G. Marin

Published online: October 17, 2025

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doi:10.14218/JCTH.2025.00329

Immunoglobulin G4-related Autoimmune Hepatitis: Diagnosis and Treatment

Fang Wei, Jiping Zhang, Xuan An

Published online: September 28, 2025

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doi:10.14218/JCTH.2025.00288

Hot Topic Commentary

Intrahepatic Cholestasis of Pregnancy: A Hot Topic Commentary

Bianca Thakkar, George Y. Wu

Published online: September 22, 2025

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doi:10.14218/JCTH.2025.00381

Consensus

Consensus on the Management of Liver Injury Associated with Targeted Drugs and Immune Checkpoint Inhibitors for Hepatocellular Carcinoma (Version 2024)

Suxian Zhao, Jie Li, Lingdi Liu, Sha Huang, Yanhang Gao, Mei Liu, Yu Chen, Lai Wei, Jidong Jia, Hong You, Zhongping Duan, Hui Zhuang, Jingfeng Liu, Xiaoyuan Xu, Yuemin Nan, Chinese Society of Hepatology, Chinese Medical Association

Published online: September 12, 2025

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doi:10.14218/JCTH.2025.00228

Expert Consensus on Clinical Applications of Fecal Microbiota Transplantation for Chronic Liver Disease (2025 edition)

Yongjian Zhou, Li Yang, Yuemin Nan, Liver Related Digestive Diseases Group, Chinese Society of Hepatology, Chinese Medical Association

Published online: October 27, 2025

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doi:10.14218/JCTH.2025.00456

Mini Review

The Mechanisms behind Thrombocytopenia in Patients with Portal Hypertension and Chronic Liver Disease

Valeria M. Fernández-Garibay, Mariana M. Ramírez-Mejia, Guadalupe Ponciano-Rodriguez, Ran Wang, Xingshun Qi, Nahum Méndez-Sánchez

Published online: September 3, 2025

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doi:10.14218/JCTH.2025.00279

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