Original Article

SOX9 Overexpression Ameliorates Metabolic Dysfunction-associated Steatohepatitis Through Activation of the AMPK Pathway Juan Deng, Kai Ding, Shuqing Liu, Fei Chen, Ru Huang, Bonan Xu, Xin Zhang, Weifen Xie Published online: December 20, 2024 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2024.00197

Dose-dependent Relationship between Alcohol Consumption and the Risks of Hepatitis B Virus-associated Cirrhosis and Hepatocellular Carcinoma: A Meta-analysis and Systematic Review Yin-Ping Wu, Xue-Yan Yang, Yu-Xin Tian, Jin Feng, Yee Hui Yeo, Fan-Pu Ji, Ming-Hua Zheng, Yu-Chen Fan Published online: December 17, 2024 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2024.00379

HBx Facilitates Drug Resistance in Hepatocellular Carcinoma via CD133-regulated Self-renewal of Liver Cancer Stem Cells Xiangshu Jin, Huijun Dong, Juan Wang, Guomin Ou, Xinyuan Lai, Xing Tian, Lei Wang, Hui Zhuang, Tong Li, Kuanhui Xiang Published online: November 25, 2024 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2024.00259

Burden of Liver Cancer Attributable to Hepatitis B and Alcohol Globally, in China, and for Five Sociodemographic Index Regions from 1990 to 2021: A Population-based Study Xiuxiu Deng, Hui Li, Yuru Zhong, Haibo Wang, Lixin Ke, Zhifei Wang, Alexios-Fotios A. Mentis, Yangqin Xun, Qiang Zhang, Cuncun Lu Published online: November 11, 2024 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2024.00351

Evaluation of Plasma Neurodegenerative Biomarkers for Diagnosing Minimal Hepatic Encephalopathy and Predicting Overt Hepatic Encephalopathy in Chinese Patients with Hepatic Cirrhosis Qiuyu Cheng, Yunhui Liu, Zhongyuan Yang, Meng Zhang, Tingting Liu, Yuxin Niu, Wei Liu, Lanyue Huang, Yuzhao Feng, Xiaoyun Zhang, Xiaoping Luo, Qin Ning, Tao Chen Published online: December 12, 2024 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2024.00413

Risk of Coronary Artery Disease in Patients with Liver Cirrhosis: A Systematic Review and Meta-analysis Chunru Gu, Liyan Dong, Lu Chai, Zhenhua Tong, Fangbo Gao, Walter Ageno, Fernando Gomes Romeiro, Xingshun Qi Published online: November 21, 2024 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2024.00226

Sodium Butyrate Inhibits Necroptosis by Regulating MLKL via E2F1 in Intestinal Epithelial Cells of Liver Cirrhosis Yimeng Zhou, Yang Ding, Yanwei Li, Qiuju Sheng, Chao Han, Yaoxin Fan, Ziyi Wang, Bingchao Lu, Xiaoguang Dou, Chong Zhang Published online: November 8, 2024 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2024.00221

Peripheral Blood CD4+/CD8+ T Cell Ratio Predicts HBsAg Clearance in Inactive HBsAg Carriers Treated with Peginterferon Alpha Fengping Wu, Chenrui Liu, Ling He, Yikai Wang, Xin Zhang, Miaoxian Li, Rui Lu, Pei Kang, Mei Li, Yaping Li, Xiaoli Jia, Shuangsuo Dang Published online: December 6, 2024 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2024.00240

ADAMTS13 Improves Hepatic Platelet Accumulation in Pyrrolizidine Alkaloids-induced Liver Injury Mingyan Ji, Yun Chen, Yifan Ma, Dongping Li, Jin Ren, Hongyue Jiang, Sinuo Chen, Xiaoqing Zeng, Hong Gao Published online: November 22, 2024 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2024.00233

Plasma Extracellular Vesicle-derived MicroRNA Associated with Human Alpha-1 Antitrypsin Deficiency-mediated Liver Disease Regina Oshins, Zhiguang Huo, Zachary Greenberg, Virginia Clark, Sergio Duarte, Huiping Zhou, Jesse West, Mei He, Mark Brantly, Nazli Khodayari Published online: November 19, 2024 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2024.00253

Review Article

Exosome-mediated Crosstalk in the Tumor Immune Microenvironment: Critical Drivers of Hepatocellular Carcinoma Progression Yifei Ge, Lixue Jiang, Qingfu Dong, Yi Xu, Judy Wai Ping Yam, Xiangyu Zhong Published online: November 28, 2024 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2024.00302

The Development and Appraisal of MELD 3.0 in Liver Diseases: Good Things Never Come Easy Gaoyue Guo, Wanting Yang, Jia Li, Ziyi Yang, Jing Liang, Chao Sun Published online: November 12, 2024 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2024.00303

T-cell Receptor Repertoire Analysis in the Context of Transarterial Chemoembolization Synergy with Systemic Therapy for Hepatocellular Carcinoma Jie Li, Yuyuan Zhang, Luqi Hu, Heqing Ye, Xingli Yan, Xin Li, Yifan Li, Shuwen Ye, Bailu Wu, Zhen Li Published online: November 12, 2024 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2024.00238

Current Status of Glucagon-like Peptide-1 Receptor Agonists in Metabolic Dysfunction-associated Steatotic Liver Disease: A Clinical Perspective Ming-Wang Wang, Lun-Gen Lu Published online: November 6, 2024 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2024.00271

Illuminating and Instructive Clinical Case

Virological Response to Lamivudine and Tenofovir Treatment in a Mono-infected Chronic Hepatitis B Patient with Potential Tenofovir Resistance: A Case Report Monica Dahiya, Teresa Tai, Trana Hussaini, Gordon Ritchie, Nancy Matic, Eric M. Yoshida, Christopher F. Lowe Published online: December 12, 2024 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2024.00248

Ferrochelatase Gene Variants Associated with Cholestasis in Adults: A Case Report Xiaona Lu, Kun Liu, Wenlan Zheng, Xuemei Zhang, Jia Shi, Shihan Yu, Yueqiu Gao, Hai Feng, Zhuo Yu Published online: November 28, 2024 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2024.00304

Research Letter

Delay in Paracentesis and Clinical Outcomes in Hospitalized Patients with Cirrhosis and Ascites Ashwani K. Singal, Yong-Fang Kuo Published online: November 11, 2024 [ Html ] [ PDF ] [ Google Scholar ] [ Cite ] doi:10.14218/JCTH.2024.00332