Xia & He Publishing

Original Article

Infectious Hepatitis

Global Trends and Cross-country Inequalities of Acute Hepatitis E in the Elderly, 1990–2021: A Comprehensive Analysis

Deliang Huang, Jinyan Jiang, Jinghan Peng, Zhibin Zhu, Yuanyuan Chen, Siyu Zhang, Huiyi Lai, Hong Yu, Qi Zhao, Yanna Wu, Yanping Chen, Jun Chen

Published online: May 30, 2025

[ Html ] [ PDF Pages: 609-618 ] [ Google Scholar ] [ Cite ]

doi:10.14218/JCTH.2025.00101

Liver Injury, Autoimmune, and Cholestatic Diseases

Integrated Analysis of Serum and Fecal Metabolites Reveals the Role of Bile Acid Metabolism in Drug-induced Liver Injury: Implications for Diagnostic and Prognostic Biomarkers

Simiao Yu, Sici Wang, Ping Li, Haocheng Zheng, Jing Jing, Tingting He, Xia Ding, Ruilin Wang

Published online: June 30, 2025

[ Html ] [ PDF Pages: 619-629 ] [ Google Scholar ] [ Cite ]

doi:10.14218/JCTH.2025.00073

Hepatic and Biliary Neoplasia

ATOX1 Promotes Hepatocellular Carcinoma Carcinogenesis via Activation of the c-Myb/PI3K/AKT Signaling Pathway

Qin Ouyang, Siyu Jia, Qianyu Zhu, Yanmeng Li, Huaduan Zi, Sisi Chen, Pingping He, Hengcheng Tang, Yanling Li, Anjian Xu, Bei Zhang, Xiaomin Wang, Xiaojuan Ou, Donghu Zhou, Jian Huang

Published online: July 7, 2025

[ Html ] [ PDF Pages: 630-643 ] [ Google Scholar ] [ Cite ]

doi:10.14218/JCTH.2024.00422

Liver Failure, Cirrhosis and Portal Hypertension

Clinical, Microbiological, and Antibiotic Treatment Characteristics of Bacterial Infections in Patients with Liver Cirrhosis in China: A Multicenter Study

Xiuding Zhang, Haoda Weng, Qinzhi Deng, Min Deng, Xuwei Wu, Zuxiong Huang, Shourong Liu, Rui Wu, Chunlian Ma, Yao Xu, Jianfeng Zhong, Jie Yang, Yinxia Wu, Huajiang Shen, Feng Ding, Fang Wang, Xuezhen Zhai, Chunxian Peng, Haotang Ren, Jie Jin, Xiangfei Xu, Xiaofei Li, Xiaoting Ye, Guoqing Qian, Shuilin Sun, Xuebing Yao, Haifeng Miao, Qianggu Xiao, Shaoheng Ye, Qing Zhang, Xinyi Xu, Xia Yu, Yue Yu, Yan Lan, Huilan Tu, Xianbin Xu, Xinrong Zhang, Rui Huang, Xiaohan Qian, Qiao Yang, Jifang Sheng, Yu Shi

Published online: July 3, 2025

[ Html ] [ PDF Pages: 644-654 ] [ Google Scholar ] [ Cite ]

doi:10.14218/JCTH.2025.00211

Adrenomedullin as an Immunomodulator of CD14⁺MerTK⁺ Circulating Monocytes in Liver Failure Syndromes

Francesca Maria Trovato, Florent Artru, Roosey Sheth, Rima Abdalla, Joseph Wilson, Anna Broderick, John Smith, Stephen Atkinson, Mark J. McPhail

Published online: June 24, 2025

[ Html ] [ PDF Pages: 655-664 ] [ Google Scholar ] [ Cite ]

doi:10.14218/JCTH.2025.00074

Review Article

Targeting Glypican-3 for Liver Cancer Therapy: Clinical Applications and Detection Methods

Jin Zhang, Rong Li, Xueqin Tan, Chuang Wang

Published online: August 7, 2025

[ Html ] [ PDF Pages: 665-681 ] [ Google Scholar ] [ Cite ]

doi:10.14218/JCTH.2025.00099

Orphan Nuclear Receptors in Metabolic Dysfunction-associated Steatotic Liver Disease Development

Huan Li, Jian Chen, Ziyin Huang, Mingkai Chen

Published online: June 19, 2025

[ Html ] [ PDF Pages: 682-692 ] [ Google Scholar ] [ Cite ]

doi:10.14218/JCTH.2025.00019

Acute Liver Failure with Determinate rather than Indeterminate Etiology Facilitates Therapy and May Avoid Liver Transplantation: A Critical Analysis

Rolf Teschke, Axel Eickhoff