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Original Article

Metabolic Liver Diseases

Discrepancies between Nonalcoholic and Metabolic-associated Fatty Liver Disease by Multiple Steatosis Assessment

Congxiang Shao, Junzhao Ye, Xin Li, Yansong Lin, Shiting Feng, Bing Liao, Wei Wang, Xiaorong Gong, Bihui Zhong

Published online: February 24, 2022

[ ] [ PDF Pages: 1013-1026 ] [ Google Scholar ] [ Cite ]

doi:10.14218/JCTH.2021.00371

Development and Validation of a Nomogram for Prediction of the Risk of MAFLD in an Overweight and Obese Population

Di Song, Qian Ge, Ming Chen, Song Bai, Xiaoshu Lai, Gege Huang, Mengmeng Liu, Miaofang Lin, Jinfeng Xu, Fajin Dong

Published online: February 28, 2022

[ ] [ PDF Pages: 1027-1033 ] [ Google Scholar ] [ Cite ]

doi:10.14218/JCTH.2021.00317

Association between Metabolic Dysfunction-associated Fatty Liver Disease and Cognitive Impairment

Qiang Yu, Ruixin He, Haowen Jiang, Ji Wu, Zhifeng Xi, Kang He, Yongbo Liu, Tao Zhou, Mingxuan Feng, Ping Wan, Hexin Yan, Qiang Xia

Published online: February 17, 2022

[ ] [ PDF Pages: 1034-1041 ] [ Google Scholar ] [ Cite ]

doi:10.14218/JCTH.2021.00490

A Class Effect Network Meta-analysis of Lipid Modulation in Non-alcoholic Steatohepatitis for Dyslipidemia

Jieling Xiao, Cheng-Han Ng, Yip-Han Chin, Darren Jun Hao Tan, Wen-Hui Lim, Grace Lim, Jingxuan Quek, Ansel Shao Pin Tang, Kai-En Chan, Rou-Yi Soong, Nicholas Chew, Benjamin Tay, Daniel Q. Huang, Nobuharu Tamaki, Roger Foo, Mark Y. Chan, Mazen Noureddin, Mohammad Shadab Siddiqui, Arun J. Sanyal, Mark D. Muthiah

Published online: May 30, 2022

[ ] [ PDF Pages: 1042-1049 ] [ Highlights ] [ Google Scholar ] [ Equator Checklist ] [ COI Form ] [ Cite ]

doi:10.14218/JCTH.2022.00095

Quzhi Formula Alleviates Nonalcoholic Steatohepatitis by Impairing Hepatocyte Lipid Accumulation and Inflammation via Bip/eIF2α Signaling

Yue-Lan Wu, Jiao-Xiang Wu, Ting-Ting Shen, Hai-Sheng Chai, Hui-Fen Chen, Qin Zhang

Published online: February 24, 2022

[ ] [ PDF Pages: 1050-1058 ] [ Google Scholar ] [ Cite ]

doi:10.14218/JCTH.2021.00458

Infectious Hepatitis

Soluble CD163 and CD163 Expression on Monocytes Associated with Chronic Hepatitis B Inflammation and HBsAg Loss

Peilin Xie, Bilian Yao, Dao Huang, Yongyan Chen, Qiming Gong, Xinxin Zhang

Published online: February 28, 2022

[ ] [ PDF Pages: 1059-1067 ] [ Google Scholar ] [ Cite ]

doi:10.14218/JCTH.2021.00496

ACE Score Identifies HBeAg-negative Inactive Carriers at a Single-point Evaluation, Regardless of HBV Genotype

Luisa Roade, Mar Riveiro-Barciela, Adriana Palom, Francisco Rodríguez-Frías, Marta Bes, Ariadna Rando, María Teresa Salcedo, Rosario Casillas, Elena Vargas-Accarino, David Tabernero, Silvia Sauleda, Rafael Esteban, María Buti

Published online: April 24, 2022

[ ] [ PDF Pages: 1068-1076 ] [ Google Scholar ] [ Cite ]

doi:10.14218/JCTH.2022.00068

Direct-acting Antiviral-induced Transient Recovery of NK Cells in Early-stage Treatment of Chronic Hepatitis C Patients

Xiaohui Zhang, Yingying Jiang, Shaobin Li, Dandan Bian, Mei Liu, Ming Kong, Yu Chen, Zhongping Duan, Sujun Zheng

Published online: February 9, 2022

[ ] [ PDF Pages: 1117-1124 ] [ Google Scholar ] [ Cite ]

doi:10.14218/JCTH.2021.00427

DILI, Autoimmune, and Cholestatic Diseases

FOXO1 Alleviates Liver Ischemia-reperfusion Injury by Regulating the Th17/Treg Ratio through the AKT/Stat3/FOXO1 Pathway

Hao-Zhen Ren, Sen-Zhe Xia, Xue-Qian Qin, An-Yin Hu, Jing-Lin Wang

Published online: March 15, 2022

[ ] [ PDF Pages: 1138-1147 ] [ Google Scholar ] [ Cite ]

doi:10.14218/JCTH.2021.00551

Calcineurin Inhibitors in the Treatment of Adult Autoimmune Hepatitis: A Systematic Review

Martine AMC Baven-Pronk, Joffre M. Hew, Maaike Biewenga, Maarten E. Tushuizen, Aad P. van den Berg, Gerd Bouma, Johannes T. Brouwer, Bart van Hoek, Dutch Autoimmune Hepatitis Study Group

Published online: March 25, 2022

[ ] [ PDF Pages: 1155-1166 ] [ Google Scholar ] [ Cite ]

doi:10.14218/JCTH.2021.00535

Preclinical Long-term Magnetic Resonance Imaging Study of Silymarin Liver-protective Effects

Yeon Ji Chae, Hwon Heo, Chul-Woong Woo, Sang-Tae Kim, Jae-Im Kwon, Monica Young Choi, Yu Sub Sung, Kyung Won Kim, Jeong Kon Kim, Yoonseok Choi, Dong-Cheol Woo

Published online: April 13, 2022

[ ] [ PDF Pages: 1167-1175 ] [ Google Scholar ] [ Cite ]

doi:10.14218/JCTH.2021.00499

Liver Failure, Cirrhosis and Portal Hypertension

Noninvasive Assessment of Liver Fibrosis and Inflammation in Chronic Hepatitis B: A Dual-task Convolutional Neural Network (DtCNN) Model Based on Ultrasound Shear Wave Elastography

Chengyan Wang, Lili Zheng, Yan Li, Shujun Xia, Jun Lv, Xumei Hu, Weiwei Zhan, Fuhua Yan, Ruokun Li, Xinping Ren

Published online: March 29, 2022

[ ] [ PDF Pages: 1077-1085 ] [ Google Scholar ] [ Cite ]

doi:10.14218/JCTH.2021.00447

Retrorsine Cooperates with Gut Microbiota to Promote Hepatic Sinusoidal Obstruction Syndrome by Disrupting the Gut Barrier

Li Xiao, Lilin Hu, Huikuan Chu, Liuying Chen, Jingjing Yan, Weijun Wang, Xiaoqian Yang, Qingjing Zhu, Fan Du, Yuhu Song, Peng Chen, Xiaohua Hou, Ling Yang

Published online: March 11, 2022

[ ] [ PDF Pages: 1086-1098 ] [ Google Scholar ] [ Cite ]

doi:10.14218/JCTH.2021.00398

Effects of Low-dose and High-dose Rifaximin in the Treatment of Covert Hepatic Encephalopathy

Wei Tan, Jian Wang, Pei-Mei Shi, Ling-Mei Feng, Jian Shi, Bei-Fang Ning, Zong-Li Yuan, Xin Zeng, Wei-Fen Xie

Published online: February 14, 2022

[ ] [ PDF Pages: 1099-1106 ] [ Google Scholar ] [ Cite ]

doi:10.14218/JCTH.2021.00457

O-GlcNAcylation Coordinates Glutaminolysis by Regulating the Stability and Membrane Trafficking of ASCT2 in Hepatic Stellate Cells

Feixia Wang, Li Chen, Biyun Zhang, Zhanghao Li, Min Shen, Li Tang, Zili Zhang, Jiangjuan Shao, Feng Zhang, Shizhong Zheng, Shanzhong Tan

Published online: March 11, 2022

[ ] [ PDF Pages: 1107-1116 ] [ Google Scholar ] [ Cite ]

doi:10.14218/JCTH.2021.00413

Gasdermin D Inhibitor Necrosulfonamide Alleviates Lipopolysaccharide/D-galactosamine-induced Acute Liver Failure in Mice

Yi-Long Wu, Wei-Jie Ou, Ming Zhong, Su Lin, Yue-Yong Zhu

Published online: March 8, 2022

[ ] [ PDF Pages: 1148-1154 ] [ Google Scholar ] [ Cite ]

doi:10.14218/JCTH.2021.00560

Hepatic and Biliary Neoplasia

Krüppel-like Factor 13 Promotes HCC Progression by Transcriptional Regulation of HMGCS1-mediated Cholesterol Synthesis

Chao-Chun Chen, Xing-Ming Xie, Xue-Ke Zhao, Shi Zuo, Hai-Yang Li

Published online: March 7, 2022

[ ] [ PDF Pages: 1125-1137 ] [ Google Scholar ] [ Cite ]

doi:10.14218/JCTH.2021.00370

Review Article

Role of Small Extracellular Vesicles in Liver Diseases: Pathogenesis, Diagnosis, and Treatment

Tingmao Xue, Judy Wai Ping Yam

Published online: June 28, 2022

[ ] [ PDF Pages: 1176-1185 ] [ Highlights ] [ Google Scholar ] [ COI Form ] [ Cite ]

doi:10.14218/JCTH.2022.00008

Therapeutic Perspectives of IL1 Family Members in Liver Diseases: An Update

Ines Bilić Ćurčić, Tomislav Kizivat, Ana Petrović, Robert Smolić, Ashraf Tabll, George Y. Wu, Martina Smolić

Published online: August 15, 2022

[ ] [ PDF Pages: 1186-1193 ] [ Highlights ] [ Google Scholar ] [ COI Form ] [ Cite ]

doi:10.14218/JCTH.2021.00501

Immunotherapy-induced Hepatotoxicity: A Review

Teresa Da Cunha, George Y. Wu, Haleh Vaziri

Published online: July 22, 2022

[ ] [ PDF Pages: 1194-1204 ] [ Highlights ] [ Google Scholar ] [ COI Form ] [ Cite ]

doi:10.14218/JCTH.2022.00105

P2X7 Receptor in Alcoholic Steatohepatitis and Alcoholic Liver Fibrosis

Guo-Qing Xia, Qian Fang, Jun-Nan Cai, Zi-Xuan Li, Feng-Zhi Zhang, Xiong-Wen Lv

Published online: May 17, 2022

[ ] [ PDF Pages: 1205-1212 ] [ Google Scholar ] [ COI Form ] [ Cite ]

doi:10.14218/JCTH.2022.00022

Sarcopenia in Chronic Liver Disease: A Metabolic Perspective

Ramesh Kumar, Sabbu Surya Prakash, Rajeev Nayan Priyadarshi, Utpal Anand

Published online: August 9, 2022

[ ] [ PDF Pages: 1213-1222 ] [ Highlights ] [ Google Scholar ] [ COI Form ] [ Cite ]

doi:10.14218/JCTH.2022.00239

Pre-emptive TIPSS in Acute Variceal Bleeding: Current Status, Controversies, and Future Directions

Yu Jun Wong, Wei Ling Danielle Ho, Juan G. Abraldes

Published online: July 29, 2022

[ ] [ PDF Pages: 1223-1228 ] [ Highlights ] [ Google Scholar ] [ COI Form ] [ Cite ]

doi:10.14218/JCTH.2022.00240

Fatty Pancreas: Linking Pancreas Pathophysiology to Nonalcoholic Fatty Liver Disease

Manus Rugivarodom, Tanawat Geeratragool, Nonthalee Pausawasdi, Phunchai Charatcharoenwitthaya

Published online: July 14, 2022

[ ] [ PDF Pages: 1229-1239 ] [ Google Scholar ] [ COI Form ] [ Cite ]

doi:10.14218/JCTH.2022.00085

Illuminating and Instructive Clinical Case

Sarcomatoid Intrahepatic Cholangiocarcinoma After Immunotherapy: A Case Report and Review of the Literature

Zheng Zeng, Yu Liu, Jing Yu, Qiang Xu, Yong Wang, Chang Zhao, Ou Jiang

Published online: March 2, 2022

[ ] [ PDF Pages: 1240-1249 ] [ Google Scholar ] [ Cite ]

doi:10.14218/JCTH.2021.00395

Reviewer Acknowledgement

2022 Reviewer Acknowledgement

Editorial Office of Journal of Clinical and Translational Hepatology

Published online: December 28, 2022

[ ] [ PDF Pages: 1250-1254 ] [ Google Scholar ] [ Cite ]

doi:10.14218/JCTH.2022.000RA

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