Original Article

TF-rs1049296 C>T Variant Modifies the Association between Hepatic Iron Stores and Liver Fibrosis in Metabolic Dysfunction-associated Steatotic Liver Disease Sui-Dan Chen, Ka-Te Huang, Huai Zhang, Yang-Yang Li, Yi Jin, Hai-Yang Yuan, Pei-Wu Zhu, Jian-Min Li, Christopher D. Byrne, Giovanni Targher, Ming-Hua Zheng Published online: December 11, 2025 [ Html ] [ PDF Pages: 1-10 ] [ Google Scholar ] [ Cite ] J Clin Transl Hepatol. 2025;14(1):1-10.  doi:10.14218/JCTH.2025.00305

Oxytocin Attenuates Metabolic Dysfunction-associated Steatotic Liver Disease via AMPK/SREBP1c/FAS-mediated Suppression of Hepatic Lipogenesis Yue Xu, Siqian Lu, Hongpei Wu, Haifeng Wu, Ming Li, Meng Zhou, Ting Chen, Xun Wang, Lishuai Qu, Qin Jin, Jinxia Liu Published online: November 26, 2025 [ Html ] [ PDF Pages: 11-22 ] [ Google Scholar ] [ Cite ] J Clin Transl Hepatol. 2025;14(1):11-22.  doi:10.14218/JCTH.2025.00213

Extrahepatic Autoimmune Diseases in Autoimmune Hepatitis: Their Prevalence, Predictors, and Influence on Early Treatment Outcomes Yue-Yang Ma, Wei-Hao Zhao, Ke-Ying Ou, Jia-Nan Cui, Chuan-Su Yuan, Bin Liu, Yong-Feng Yang, Qing-Fang Xiong Published online: January 15, 2026 [ Html ] [ PDF Pages: 23-30 ] [ Google Scholar ] [ Cite ] J Clin Transl Hepatol. 2026;14(1):23-30.  doi:10.14218/JCTH.2025.00424

Serum Interleukin-8 for Differentiating Invasive Pulmonary Aspergillosis from Bacterial Pneumonia in Patients with HBV-Associated Acute-on-Chronic Liver Failure Lanyue Huang, Yuzhao Feng, Wei Wang, Wei Liu, Yunhui Liu, Liang Chen, Yuxin Niu, Tingting Liu, Mi Song, Yiwei Xu, Zhongyuan Yang, Guang Chen, Qin Ning, Tao Chen, Lin Zhu Published online: December 26, 2025 [ Html ] [ PDF Pages: 31-38 ] [ Google Scholar ] [ Cite ] J Clin Transl Hepatol. 2025;14(1):31-38.  doi:10.14218/JCTH.2025.00645

Genotype-specific Response to 144-week Entecavir Therapy for HBeAg-positive Chronic Hepatitis B with a Particular Focus on Histological Improvement: A Prospective Study Lexin Liu, Qiumiao Xu, Shanshan Lin, Zehui Wei, Guoxin Huang Published online: December 31, 2025 [ Html ] [ PDF Pages: 39-49 ] [ Google Scholar ] [ Cite ] J Clin Transl Hepatol. 2025;14(1):39-49.  doi:10.14218/JCTH.2025.00533

Review Article

ATP-binding Cassette Transporter Defects and Their Roles in Hepatic Diseases Danzhu Zhao, George Y. Wu Published online: December 18, 2025 [ Html ] [ PDF Pages: 50-58 ] [ Google Scholar ] [ Cite ] J Clin Transl Hepatol. 2025;14(1):50-58.  doi:10.14218/JCTH.2025.00476

Applications of Artificial Intelligence and Smart Devices in Metabolic Dysfunction-associated Steatotic Liver Disease Wenfeng Zhu, Qi Zheng, Xinyi Xu, Xia Yu, Xianbin Xu, Huilan Tu, Yue Yu, Wubing Ying, Jiahao Xie, Guoping Sheng, Jifang Sheng Published online: December 11, 2025 [ Html ] [ PDF Pages: 59-75 ] [ Google Scholar ] [ Cite ] J Clin Transl Hepatol. 2025;14(1):59-75.  doi:10.14218/JCTH.2025.00406

Primary Biliary Cholangitis–associated Osteoporosis: Contemporary Review of Pathogenesis and Management Jiaqi Yang, Shuhao Su, Ting Yuan, Caiyun Yang, Jie Luo, Xingchen Liu, Guanya Guo, Changcun Guo, Ying Han Published online: January 14, 2026 [ Html ] [ PDF Pages: 76-82 ] [ Google Scholar ] [ Cite ] J Clin Transl Hepatol. 2026;14(1):76-82.  doi:10.14218/JCTH.2025.00505

Consensus

Expert Consensus on the Diagnosis and Management of Inherited Hyperbilirubinemia (2025) Sujun Zheng, Xiaoyuan Xu, Yuemin Nan, Wei Hou, Jie Bai, Shan Tang, Chen Liang, Lei Luo, Jianshe Wang, Xinhua Li, Min Zhang, Guohong Deng, Hui Liu, Yongfeng Yang, Wen Xie, Xiaojuan Ou, Xinxin Zhang, Lai Wei, Jidong Jia, Zhongping Duan, Inherited Metabolic Liver Disease Collaboration Group, Chinese Society of Hepatology, Chinese Medical Association Published online: December 26, 2025 [ Html ] [ PDF Pages: 83-95 ] [ Google Scholar ] [ Cite ] J Clin Transl Hepatol. 2025;14(1):83-95.  doi:10.14218/JCTH.2025.00440

Guideline

Chinese Guidelines for Clinical Diagnosis, Treatment, and Management of Cirrhosis (2025) Xiaoyuan Xu, Huiguo Ding, Hong You, Yujuan Guan, Jinghang Xu, Wengang Li, Ying Han, Yaping Wang, Yifan Han, Jidong Jia, Lai Wei, Zhongping Duan, Yuemin Nan, Hui Zhuang, Chinese Society of Hepatology, Chinese Medical Association Published online: January 13, 2026 [ Html ] [ PDF Pages: 96-115 ] [ Google Scholar ] [ Cite ] J Clin Transl Hepatol. 2026;14(1):96-115.  doi:10.14218/JCTH.2025.00517

Research Letter

Hepatitis C Patient Education: Large Language Models Show Promise in Disseminating Guidelines Jinyan Chen, Ruijie Zhao, Chiyu He, Huigang Li, Yajie You, Zuyuan Lin, Ze Xiang, Jianyong Zhuo, Wei Shen, Zhihang Hu, Shusen Zheng, Xiao Xu, Di Lu Published online: December 18, 2025 [ Html ] [ PDF Pages: 116-119 ] [ Google Scholar ] [ Cite ] J Clin Transl Hepatol. 2025;14(1):116-119.  doi:10.14218/JCTH.2025.00238