Original Article

Chronic Hepatitis B in the Asia-Pacific Region: Results of the 2023 Global Burden of Disease Study Zhengzhao Lu, Dong Xu, Wei Ji, Jingjie Zhao, Tingting Xiao, Dongxu Wang, Yuanyuan Kong, Jidong Jia, Hong You, Xinyu Zhao Published online: June 26, 2026 [ Html ] [ PDF Pages: 587-600 ] [ Google Scholar ] [ Cite ] J Clin Transl Hepatol. 2026;14(6):587-600.  doi:10.14218/JCTH.2026.00114

Regional Inequities in Metabolic Dysfunction–associated Steatotic Liver Disease Burden and Care Quality in High-burden Settings: Implications for Health Systems Kexin Zhang, Chengxia Kan, Sufang Sheng, Wei Xu, Fang Han, Jian Chen, Xuan Li, Ningning Hou, Ying Xue, Xiaodong Sun Published online: June 22, 2026 [ Html ] [ PDF Pages: 601-612 ] [ Google Scholar ] [ Cite ] J Clin Transl Hepatol. 2026;14(6):601-612.  doi:10.14218/JCTH.2026.00127

GSTM3 Knockdown Promotes Liver Fibrosis Reversal by Inhibiting Hepatic Stellate Cell Activation via PPARγ Signaling Chenxue Hou, Bingqing Yang, Yuanying Zhao, Hao Chang, Tong Bu, Qi Wang, Yue Li Published online: May 25, 2026 [ Html ] [ PDF Pages: 613-627 ] [ Google Scholar ] [ Cite ] J Clin Transl Hepatol. 2026;14(6):613-627.  doi:10.14218/JCTH.2025.00658

A Dual Time Window-driven Strategy to Optimize Primary Biliary Cholangitis Treatment via Alkaline Phosphatase Normalization Han Zhao, Yansheng Liu, Yingmei Tang, Ningning Wang, Yanmin Liu, Yiling Li, Chunyang Huang, Jieting Duan, Yan Feng, Linhua Zheng, Ruiqing Sun, Xiufang Wang, Juan Deng, Gui Jia, Patrick S.C. Leung, M. Eric Gershwin, Yulong Shang, Ying Han Published online: May 15, 2026 [ Html ] [ PDF Pages: 628-636 ] [ Google Scholar ] [ Cite ] J Clin Transl Hepatol. 2026;14(6):628-636.  doi:10.14218/JCTH.2026.00082

A Multi-omics and Machine Learning Framework Identifies Plasma SBDS as a Causal Biomarker and Therapeutic Target in Primary Sclerosing Cholangitis Pengfei Cheng, Yuanming Qiang, Yibo Sun, Binwei Duan, Yabo Ouyang, Guangming Li Published online: March 20, 2026 [ Html ] [ PDF Pages: 637-648 ] [ Google Scholar ] [ Cite ] J Clin Transl Hepatol. 2026;14(6):637-648.  doi:10.14218/JCTH.2025.00676

Targeting the 4EBP1/HSP90β/Nrf2 Axis Sensitizes β-catenin-mutant Hepatocellular Carcinoma to mTOR Inhibitors via Ferroptosis Induction Rong Li, Yi Zhou, Zimu Wang, Gang Liu, Deyu Fan, Lanxuan Huang, Fule Deng, Ning Wei, Runze Shang, Meng Xu Published online: June 16, 2026 [ Html ] [ PDF Pages: 649-664 ] [ Google Scholar ] [ Cite ] J Clin Transl Hepatol. 2026;14(6):649-664.  doi:10.14218/JCTH.2026.00072

Review Article

Antimitochondrial Antibody Measurements in the Diagnosis of Antimitochondrial Antibody-negative and Alkaline Phosphatase-positive Primary Biliary Cholangitis: An Update and Review Karol Suchowiecki, George Y. Wu Published online: June 23, 2026 [ Html ] [ PDF Pages: 665-673 ] [ Google Scholar ] [ Cite ] J Clin Transl Hepatol. 2026;14(6):665-673.  doi:10.14218/JCTH.2026.00117

Reducing the Risk of Overt Hepatic Encephalopathy Recurrence: A Narrative Review Nikolaos T. Pyrsopoulos, Nadege Gunn, Prasun K. Jalal, George E. Catinis Published online: May 8, 2026 [ Html ] [ PDF Pages: 674-686 ] [ Google Scholar ] [ Cite ] J Clin Transl Hepatol. 2026;14(6):674-686.  doi:10.14218/JCTH.2025.00698

Short-chain Fatty Acids and Bile Acids Signaling in Chronic Hepatitis B Siqi Sun, Sisi Yang, Yihe Yu, Jiyang Chen, Jintao Ning, Yida Yang, Hongyu Jia Published online: April 28, 2026 [ Html ] [ PDF Pages: 687-696 ] [ Google Scholar ] [ Cite ] J Clin Transl Hepatol. 2026;14(6):687-696.  doi:10.14218/JCTH.2026.00118

Letter to the Editor

Letter to the Editor: Genotype-specific Response to 144-week Entecavir Therapy for HBeAg-positive Chronic Hepatitis B with a Particular Focus on Histological Improvement: A Prospective Study Chenhao Ye, Lei Wang Published online: April 27, 2026 [ Html ] [ PDF Pages: 697-698 ] [ Google Scholar ] [ Cite ] J Clin Transl Hepatol. 2026;14(6):697-698.  doi:10.14218/JCTH.2026.00159 VIEW RELATED CONTENT : Genotype-specific Response to 144-week Entecavir Therapy for HBeAg-positive Chronic Hepatitis B with a Particular Focus on Histological Improvement: A Prospective Study Lexin Liu, Qiumiao Xu, Shanshan Lin, Zehui Wei, Guoxin Huang